Compound Q&A

How is 1-Methyl-4-(1,1,2,2-tetrafluoroethoxy)benzene (CAS: 1737-11-7) typically synthesized?

Answer

1-Methyl-4-(1,1,2,2-tetrafluoroethoxy)benzene
1-Methyl-4-(1,1,2,2-tetrafluoroethoxy)benzene (CAS: 1737-11-7) is usually synthesized via the reaction of 4-(1,1,2,2-tetrafluoroethoxy)benzene with methyl bromide in the presence of a base like sodium hydride. The reaction yields the compound in moderate to good yield, with high selectivity. The process requires careful handling and should be conducted under an inert atmosphere to prevent side reactions.

About

CAS No 1737-11-7
English Name 1-Methyl-4-(1,1,2,2-tetrafluoroethoxy)benzene
Molecular Formula C9H8F4O
Molecular Weight 208.15 g/mol
SMILES CC1=CC=C(C=C1)OC(C(F)F)(F)F
InChIKey VACIXOPZIXUAKS-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38

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