Compound Q&A
How is N-(3-Chlorophenyl)-2-pyridinecarboxamide (CAS: 61350-00-3) typically synthesized?
Answer
N-(3-Chlorophenyl)-2-pyridinecarboxamide can be synthesized through the coupling reaction of 3-chlorophenyl isocyanate with 2-pyridinecarboxamide. The synthesis typically involves heating the reactants in the presence of a catalyst such as 4-(dimethylamino)pyridine (DMAP) and a base like diisopropylethylamine (DIPEA). The yield is usually around 75-85%, and the reaction is selective and efficient.
About
CAS No
61350-00-3
English Name
N-(3-Chlorophenyl)-2-pyridinecarboxamide
Molecular Formula
C12H9ClN2O
Molecular Weight
232.67000000000002 g/mol
SMILES
C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
InChIKey
SUYUTNCKIOLMAJ-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38
