Compound Q&A

How is 2-Methyl-2-propanyl [(2R)-1-oxo-3-phenyl-2-propanyl]carbamate (CAS: 77119-85-8) typically synthesized?

Answer

2-Methyl-2-propanyl [(2R)-1-oxo-3-phenyl-2-propanyl]carbamate
2-Methyl-2-propanyl [(2R)-1-oxo-3-phenyl-2-propanyl]carbamate is typically synthesized via a Grignard reaction followed by a condensation step. The reaction involves the use of phenylmagnesium bromide with 2-methyl-2-propanol, followed by quenching with a carbamoyl chloride. The yield is moderate, and the reaction is carried out under anhydrous conditions with a suitable catalyst.

About

CAS No 77119-85-8
English Name 2-Methyl-2-propanyl [(2R)-1-oxo-3-phenyl-2-propanyl]carbamate
Molecular Formula C14H19NO3
Molecular Weight 249.31 g/mol
SMILES CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C=O
InChIKey ZJTYRNPLVNMVPQ-GFCCVEGCSA-N
Last Updated: 2025-10-26 09:38

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