Compound Q&A
How is N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide (CAS: 1118807-13-8) typically synthesized?
Answer
![N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide](https://static.chemtradehub.com/structs/111/1118807-13-8-dab1.webp "N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide")
The compound can be synthesized through a multi-step procedure involving the coupling of 3-(3,4-dimethoxyphenyl)propanoic acid and 6-chlorobenzo[d]thiazole-2-carboxylic acid using a coupling agent like HATU in the presence of a base like DIPEA. The yield is typically around 75-85% with moderate selectivity.
About
CAS No
1118807-13-8
English Name
N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide
Molecular Formula
C18H17ClN2O3S
Molecular Weight
376.8650000000001 g/mol
SMILES
COC1=C(C=C(C=C1)CCC(=O)NC2=NC3=C(S2)C=C(C=C3)Cl)OC
InChIKey
LXFKEVQQSKQXPR-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38
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