Compound Q&A

Are there alternatives to 1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate hydrate (CAS: 223652-90-2) in synthesis?

Answer

1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate hydrate (1:1:1)
There are alternative compounds that can be used as substitutes in synthesis. For example, analogs such as 1-Cyclopropyl-8-methoxy-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate hydrate can be considered. Other common alternative reagents might include difluoromethanol or other similar dihydroisoquinoline derivatives. These alternatives can offer similar functionalities with varying degrees of efficacy and cost.

About

English Name 1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate hydrate (1:1:1)
Molecular Formula C24H26F2N2O8S
Molecular Weight 540.54 g/mol
SMILES CC1C2=C(CN1)C=C(C=C2)C3=C(C4=C(C=C3)C(=O)C(=CN4C5CC5)C(=O)O)OC(F)F.CS(=O)(=O)O.O
InChIKey IGTHEWGRXUAFKF-NVJADKKVSA-N
Last Updated: 2025-10-23 17:36

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