Compound Q&A
How is 2-Chloro-3-methylisonicotinic acid (CAS: 133928-73-1) typically synthesized?
Answer
2-Chloro-3-methylisonicotinic acid is usually synthesized via the electrophilic substitution of 3-methylisonicotinic acid with chlorine. A common method involves reacting 3-methylisonicotinic acid with thionyl chloride in pyridine. The reaction is conducted at elevated temperatures to achieve good yields and good selectivity.
About
CAS No
133928-73-1
English Name
2-Chloro-3-methylisonicotinic acid
Molecular Formula
C7H6ClNO2
Molecular Weight
171.58 g/mol
SMILES
Cc1c(ccnc1Cl)C(=O)O
InChIKey
JYVLCHBMNCMRBO-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
