Compound Q&A
How is (E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide (CAS: 1357389-11-7) typically synthesized?
Answer
(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide (CAS: 1357389-11-7) is synthesized through a multi-step process involving the coupling of an amino phenyl derivative with a cinnamyl pyrazole. Commonly, this is achieved using palladium catalysis under mild conditions. The synthesis typically yields a high purity product with good selectivity and moderate to high yield depending on the specific reaction conditions.
About
CAS No
1357389-11-7
English Name
(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide
Molecular Formula
C21H19FN4O
Molecular Weight
362.41 g/mol
SMILES
C1=CC=C(C=C1)C=CCN2C=C(C=N2)C=CC(=O)NC3=C(C=C(C=C3)F)N
InChIKey
BLVQHYHDYFTPDV-VCABWLAWSA-N
Last Updated: 2025-10-23 07:31
