Compound Q&A

How is 2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione (CAS: 1218942-37-0) typically synthesized?

Answer

2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione is typically synthesized via a multi-step process involving the coupling of a 2-chloroaryl derivative with a pyrazole derivative using a palladium catalyst under microwave conditions. The yield is around 70-80%, and the product is purified by recrystallization or column chromatography.

About

English Name 2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
Molecular Formula C21H19ClN4O2
Molecular Weight 394.86 g/mol
SMILES CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
InChIKey RGYQPQARIQKJKH-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31

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