Compound Q&A

How is (2R)-3-(Stearoyloxy)-2-(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate (CAS: 20664-02-2) typically synthesized?

Answer

(2R)-3-(Stearoyloxy)-2-(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
The compound is synthesized via the condensation of stearoyl and tetradecanoyl derivatives with a trimethylammonium phospholipid. Common solvents like dichloromethane are used, with a catalyst like 4-(dimethylamino)pyridine (DMAP) to improve yield and selectivity. The reaction is typically carried out at room temperature.

About

CAS No 20664-02-2
English Name (2R)-3-(Stearoyloxy)-2-(tetradecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Molecular Formula C40H80NO8P
Molecular Weight 734 g/mol
SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCC
InChIKey MZWGYEJOZNRLQE-KXQOOQHDSA-N
Last Updated: 2025-10-23 07:31

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