Compound Q&A

How is 3-Chloro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid (CAS: 80194-18-9) typically synthesized?

Answer

3-Chloro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
3-Chloro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is typically synthesized via a multistep process involving acylation of pyridine derivatives. Commonly, acetic anhydride or acetyl chloride is used as the acylating agent, followed by chlorination and trifluoromethylation steps. High yield and high selectivity are achieved using appropriate catalysts and reaction conditions.

About

CAS No 80194-18-9
English Name 3-Chloro-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
Molecular Formula C46H44Cl3N7O9S2
Molecular Weight 1009.3721 g/mol
SMILES C1=C(C=NC(=C1Cl)C(=O)O)C(F)(F)F
InChIKey HXRMCZBDTDCCOP-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31

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