Compound Q&A
How is O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine (CAS: 198561-81-8) typically synthesized?
Answer
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O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine is typically synthesized via a multi-step process involving the protection of the threonine hydroxyl group with fluorenylmethoxycarbonyl (Fmoc) chemistry. The key steps include the synthesis of the Fmoc-protected threonine derivative followed by the coupling with benzyl and methyl groups. The reaction conditions are carefully controlled to ensure high yield and selectivity. Common solvents used include dichloromethane and triethylamine.
About
CAS No
198561-81-8
English Name
O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine
Molecular Formula
C27H27NO5
Molecular Weight
445.52 g/mol
SMILES
CC(C(C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OCC4=CC=CC=C4
InChIKey
OJELSPMZRJEODW-CJAUYULYSA-N
Last Updated: 2025-10-23 07:31
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