Compound Q&A
How is 1-Acetyl-1H-indole-3-carbaldehyde (CAS: 22948-94-3) typically synthesized?
Answer
1-Acetyl-1H-indole-3-carbaldehyde (CAS: 22948-94-3) is typically synthesized via the acetylation of indole-3-carbaldehyde. This involves the reaction of indole-3-carbaldehyde with acetic anhydride in the presence of a catalyst such as pyridine. The reaction requires careful control of temperature to achieve high selectivity and yield. The product is then purified by recrystallization or column chromatography.
About
CAS No
22948-94-3
English Name
1-Acetyl-1H-indole-3-carbaldehyde
Molecular Formula
C11H9NO2
Molecular Weight
187.2 g/mol
SMILES
CC(=O)N1C=C(C2=CC=CC=C21)C=O
InChIKey
LCJLFGSKHBDOAY-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
