Compound Q&A
How is (4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate (CAS: 1146629-77-7) typically synthesized?
Answer
![[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate](https://static.chemtradehub.com/structs/114/1146629-77-7-cdc3.webp "[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate")
(4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate can be synthesized via a multistep reaction involving the condensation of 4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid with pivaloyl chloride. The process yields a 90% yield with good selectivity. This reaction is typically performed under anhydrous conditions to optimize yield and purity.
About
CAS No
1146629-77-7
English Name
[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate
Molecular Formula
C15H17N5O2
Molecular Weight
299.33 g/mol
SMILES
CC(C)(C)C(=O)OCn1ccc2c1ncnc2c3c[nH]nc3
InChIKey
CPGIWDOJHYCMRW-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
![[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}
![[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate — Shandong Mayo Huahui Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce79492b2de6e8e95a4693/67ce79492b2de6e8e95a4693-logo.webp){kind=logo}
![[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp){kind=logo}