Compound Q&A
How is 4-(4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-piperazinyl)benzoic acid (CAS: 162046-66-4) typically synthesized?
Answer
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4-(4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-piperazinyl)benzoic acid is synthesized via a multi-step process starting from benzoic acid and 4-piperazinecarboxylic acid. Key steps include esterification, coupling, and cyclization reactions. Catalysts like EDC and DCC are used for the formation of the carbonyl ester. The overall yield is around 80%, with good selectivity towards the desired product.
About
CAS No
162046-66-4
English Name
4-(4-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-piperazinyl)benzoic acid
Molecular Formula
C16H22N2O4
Molecular Weight
306.36 g/mol
SMILES
CC(C)(C)OC(=O)N1CCN(CC1)C2=CC=C(C=C2)C(=O)O
InChIKey
BEDWYXZFIYMEJG-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
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