Compound Q&A
How is 3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrrolo[1,2-a]pyrimidin-2(3H)-yl)phenyl)-1,1-dimethylurea (CAS: 942918-07-2) typically synthesized?
Answer
![3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea](https://static.chemtradehub.com/structs/942/942918-07-2-1715.webp "3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea")
The compound is synthesized through a multistep process involving the condensation of an ethyl pyrazole with a 2-(3-(dimethylamino)methyl)phenyl-1H-pyrrolo[2,3-b]pyridine derivative. This is followed by a coupling reaction with a 4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrrolo[1,2-a]pyrimidin-2(3H)-yl)benzaldehyde, using a palladium catalyst in the presence of a base. The final step involves the formation of the urea linkage.
About
CAS No
942918-07-2
English Name
3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea
Molecular Formula
C30H33N7O
Molecular Weight
507.6420000000003 g/mol
SMILES
CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC=CC(=C5)CN(C)C
InChIKey
QTBWCSQGBMPECM-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
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