Compound Q&A
How is 2-[(4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide (CAS: 1260907-17-2) typically synthesized?
Answer
![2-[(4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide](https://static.chemtradehub.com/structs/126/1260907-17-2-2885.webp "2-[(4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide")
This compound is typically synthesized via a multistep process involving the formation of a triazole ring followed by amidation. Common catalysts include palladium(II) acetate in the presence of a phosphine ligand. The overall process is selective and yields a high purity product.
About
CAS No
1260907-17-2
English Name
2-[(4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
Molecular Formula
C22H22ClN5O2
Molecular Weight
423.9 g/mol
SMILES
CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c3cc(OC)ccc3-n4c(C)nnc14
InChIKey
AAAQFGUYHFJNHI-SFHVURJKSA-N
Last Updated: 2025-10-23 07:31
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