Compound Q&A

How is 4-Nitrophthalamide (CAS: 13138-53-9) typically synthesized?

Answer

4-Nitrophthalamide
4-Nitrophthalamide (CAS: 13138-53-9) is typically synthesized by the nitration of phthalamide using nitric acid and sulfuric acid as catalysts. The nitration process usually yields 90-95% purity. The product can be purified by recrystallization from ethanol or acetone. This synthesis method is well-documented in the literature and is known for its high yield and good selectivity.

About

CAS No 13138-53-9
English Name 4-Nitrophthalamide
Molecular Formula C8H7N3O4
Molecular Weight 209.16 g/mol
SMILES C1=CC(=C(C=C1[N+](=O)[O-])C(=O)N)C(=O)N
InChIKey XWCDSCYRIROFIO-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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