Compound Q&A

How is [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2-furyl)methanone (CAS: 19216-56-9) typically synthesized?

Answer

[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2-furyl)methanone
The compound [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2-furyl)methanone (CAS: 19216-56-9) is typically synthesized via multistep reactions involving the condensation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine with 2-furaldehyde. Commonly, this involves using sodium ethoxide as a base and ethanol as a solvent. The reaction is carried out under mild conditions to ensure high yield and selectivity.

About

CAS No 19216-56-9
English Name [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2-furyl)methanone
Molecular Formula C19H21N5O4
Molecular Weight 383.40800000000013 g/mol
SMILES COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC
InChIKey IENZQIKPVFGBNW-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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