Compound Q&A
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-L-threonine (CAS: 133180-01-5) typically synthesized?
Answer
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-L-threonine](https://static.chemtradehub.com/structs/133/133180-01-5-6c21.webp "N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-L-threonine")
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-L-threonine is synthesized via a peptide coupling reaction. Common methods include solid-phase synthesis using fluorenylmethoxycarbonyl (Fmoc) chemistry. The synthesis typically involves protecting the threonine hydroxyl group and then coupling it to the desired amino acid or peptide. The process involves careful control of pH and temperature to achieve high yields and selectivity.
About
CAS No
133180-01-5
English Name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-L-threonine
Molecular Formula
C38H33NO5
Molecular Weight
583.68 g/mol
SMILES
CC(C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6
InChIKey
JARBLLDDSTVWSM-IJAHGLKVSA-N
Last Updated: 2025-10-22 19:24
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