Compound Q&A
How is 6-Chloro-5-(chloroacetyl)-1,3-dihydro-2H-indol-2-one (CAS: 118304-3) typically synthesized?
Answer
6-Chloro-5-(chloroacetyl)-1,3-dihydro-2H-indol-2-one is typically synthesized via a multi-step process starting from indole. The key steps include chlorination, acetylation, and condensation reactions. The use of thionyl chloride and acetyl chloride as reagents facilitates the chlorination and acetylation steps, respectively. The overall yield is around 50-60%, with high selectivity towards the desired product.
About
CAS No
118307-04-3
English Name
6-Chloro-5-(chloroacetyl)-1,3-dihydro-2H-indol-2-one
Molecular Formula
C10H7Cl2NO2
Molecular Weight
244.08 g/mol
SMILES
C1C2=CC(=C(C=C2NC1=O)Cl)C(=O)CCl
InChIKey
LWWVMDRRHHCTMZ-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24
