Compound Q&A
How is 6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 98106-17-3) typically synthesized?
Answer
This compound is synthesized via a multistep process involving the protection of an alcohol, substitution reactions, and desilylation. Key reagents include silyl ethers and fluorinating agents. The final step involves the coupling of the intermediate with a piperazine derivative. The overall yield is moderate, around 50-60%, with good selectivity.
About
CAS No
98106-17-3
English Name
6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Molecular Formula
C21H19F2N3O3
Molecular Weight
399.4 g/mol
SMILES
CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F
InChIKey
NOCJXYPHIIZEHN-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24
