Compound Q&A
How is 1-Bromo-3-fluoro-5-iodobenzene (CAS: 845866-85-5) typically synthesized?
Answer
1-Bromo-3-fluoro-5-iodobenzene can be synthesized via the sequential bromination and iodination of 3-fluorobenzoic acid. The process involves the use of N-bromosuccinimide (NBS) for bromination and N-iodosuccinimide (NIS) for iodination, both catalyzed by light. The yield is typically around 70-80%, and the reaction is carried out in an inert atmosphere to prevent side reactions.
About
CAS No
845866-85-5
English Name
1-Bromo-3-fluoro-5-iodobenzene
Molecular Formula
C6H3BrFI
Molecular Weight
300.9 g/mol
SMILES
C1=C(C=C(C=C1Br)I)F
InChIKey
OQUKJSVQMVBUBY-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24
