Compound Q&A

How is 6-bromo-4-fluoro-1H-indole (CAS: 885520-59-2) typically synthesized?

Answer

6-bromo-4-fluoro-1H-indole
6-Bromo-4-fluoro-1H-indole (CAS: 885520-59-2) can be synthesized through a multistep process involving the bromination of 4-fluoro-1H-indole followed by further functional group modifications. Common synthetic methods include the use of N-bromosuccinimide (NBS) for bromination under UV light, with selectivity towards the indole ring. The overall yield of the final product is generally around 70-80%, depending on the purity of starting materials and reaction conditions.

About

English Name 6-bromo-4-fluoro-1H-indole
Molecular Formula C8H5BrFN
Molecular Weight 214.04 g/mol
SMILES C1=CNC2=C1C(=CC(=C2)Br)F
InChIKey VTODDAKQRGKCGF-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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