Compound Q&A

How is 4-Benzyl-2-(chloromethyl)morpholine (CAS: 40987-25-5) typically synthesized?

Answer

4-Benzyl-2-(chloromethyl)morpholine
4-Benzyl-2-(chloromethyl)morpholine can be synthesized by reacting benzyl bromide with morpholine in the presence of a base such as potassium carbonate. The reaction proceeds via a nucleophilic substitution, yielding the desired product with good yield and selectivity. Common solvents include dichloromethane or dimethylformamide.

About

CAS No 40987-25-5
English Name 4-Benzyl-2-(chloromethyl)morpholine
Molecular Formula C12H16ClNO
Molecular Weight 225.72 g/mol
SMILES C1COC(CN1CC2=CC=CC=C2)CCl
InChIKey GVWRZZNYCOTWNN-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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