Compound Q&A

How is (5-Chloro-2-thienyl)methanol (CAS: 74168-69-7) typically synthesized?

Answer

(5-Chloro-2-thienyl)methanol
(5-Chloro-2-thienyl)methanol is typically synthesized via a multistep process involving the reaction of 2-chlorothiophene with methanol in the presence of a suitable base like sodium methoxide. The reaction is carried out in an aprotic solvent to avoid side reactions. The yield is usually around 60-70%, and the product is purified by recrystallization.

About

CAS No 74168-69-7
English Name (5-Chloro-2-thienyl)methanol
Molecular Formula C5H5ClOS
Molecular Weight 148.614 g/mol
SMILES C1=C(SC(=C1)Cl)CO
InChIKey WMKPGPCVKFXIHD-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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