Compound Q&A

How is [(2-Propyn-1-yloxy)methyl]benzene (CAS: 4039-82-1) typically synthesized?

Answer

[(2-Propyn-1-yloxy)methyl]benzene
[(2-Propyn-1-yloxy)methyl]benzene can be synthesized through a series of reactions including the alkylation of a phenol with propyne followed by a substitution reaction. Commonly, this involves the use of sodium ethoxide in ethanol to generate the phenoxide ion, which then reacts with propyne to form the corresponding propynylphenol. Further substitution yields the final compound. The reaction typically proceeds with a yield of around 75-80%.

About

CAS No 4039-82-1
English Name [(2-Propyn-1-yloxy)methyl]benzene
Molecular Formula C10H10O
Molecular Weight 16.04 g/mol
SMILES C#CCOCC1=CC=CC=C1
InChIKey PAQVEXAFKDWGOT-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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