Compound Q&A

How is 4-(pyridin-4-yloxy)aniline (CAS: 102877-78-1) typically synthesized?

Answer

4-(pyridin-4-yloxy)aniline
4-(Pyridin-4-yloxy)aniline (CAS: 102877-78-1) can be synthesized via the condensation of 4-hydroxyaniline with 4-bromopyridine in the presence of a base such as potassium carbonate. This process requires a mild temperature and is carried out in an aqueous medium. The yield is typically around 75-85%, depending on the purity of the starting materials and reaction conditions.

About

English Name 4-(pyridin-4-yloxy)aniline
Molecular Formula C11H10N2O
Molecular Weight 186.214 g/mol
SMILES C1=CC(=CC=C1N)OC2=CC=NC=C2
InChIKey IHAFMSZIVGDZTC-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

Related Q&A

Compound Q&A

What are the physical and chemical properties of 4-(pyridin-4-yloxy)aniline (CAS: 102877-78-1)?

4-(Pyridin-4-yloxy)aniline (CAS: 102877-78-1) is a crystalline solid with a molecular weight of appr...

Compound Q&A

What industries use 4-(pyridin-4-yloxy)aniline (CAS: 102877-78-1)?

4-(Pyridin-4-yloxy)aniline (CAS: 102877-78-1) is used in the pharmaceutical industry for the synthes...

Compound Q&A

What precautions should be taken when handling 4-(pyridin-4-yloxy)aniline (CAS: 102877-78-1)?

When handling 4-(pyridin-4-yloxy)aniline (CAS: 102877-78-1), it is crucial to use appropriate person...

Compound Q&A

What precautions should be taken when handling 4-(2-Furylmethyl)thiomorpholine 1,1-dioxide (CAS: 79206-94-3)?

When handling 4-(2-Furylmethyl)thiomorpholine 1,1-dioxide (CAS: 79206-94-3), it ...

79206-94-34-(2-Furylmethyl)thi...
Compound Q&A

What precautions should be taken when handling 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide (CAS: 71320-77-9)?

When handling 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide (CAS: 71320-77-9), it...

71320-77-94-Chloro-N-[2-(4-mor...
Compound Q&A

How should waste containing 2-[2-(2-Methoxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate (CAS: 62921-74-8) be handled?

Waste containing this compound (CAS: 62921-74-8) should be handled according to ...

62921-74-82-[2-(2-Methoxyethox...
Compound Q&A

How should waste containing (S)-Methyl 2-amino-3-cyclohexylpropanoate be handled?

Waste containing (S)-Methyl 2-amino-3-cyclohexylpropanoate should be collected i...

40056-18-6(S)-Methyl 2-amino-3...