Compound Q&A
How is 4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile (CAS: 329187-59-9) typically synthesized?
Answer
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4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile is typically synthesized via a multistep process involving the reaction of 4-chloro-6-aminopyrimidine with benzonitrile in the presence of a suitable catalyst. The yield is around 70-80%, with the use of a palladium catalyst providing good selectivity.
About
CAS No
329187-59-9
English Name
4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile
Molecular Formula
C11H6Cl2N4
Molecular Weight
17.03 g/mol
SMILES
C1=CC(=CC=C1C#N)NC2=NC(=CC(=N2)Cl)Cl
InChIKey
MPEUVAXCNNGXQX-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
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