How is 1-Isothiocyanatooctadecane (CAS: 2877-26-1) typically synthesized?

1-Isothiocyanatooctadecane is typically synthesized through the reaction of 1-isonitrosooctadecane with hydrogen chloride followed by hydrolysis to form the isothiocyanate group. The reaction requires mild conditions and can be catalyzed by acids. The yield can be improved by optimizing the reaction parameters and using appropriate solvents.