Compound Q&A
How is (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride (CAS: 58895-64-0) typically synthesized?
Answer
![(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride](https://static.chemtradehub.com/structs/588/58895-64-0-6c55.webp "(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride")
The compound is typically synthesized through a multistep process involving the condensation of appropriate precursors followed by methylene insertion and hydrochloride formation. Commonly, palladium-based catalysts are used for the efficient synthesis with good yield and selectivity.
About
CAS No
58895-64-0
English Name
(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride
Molecular Formula
C21H26ClNO3
Molecular Weight
375.9 g/mol
SMILES
C=C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O.Cl
InChIKey
GYWMRGWFQPSQLK-OPHZJPRHSA-N
Last Updated: 2025-10-22 12:37
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![(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride — Wuhan Foton Weiyan Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cebe962b2de6e8e95a4b59/67cebe962b2de6e8e95a4b59-logo.webp){kind=logo}