Compound Q&A

How is 5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione (CAS: 23204-36-6) typically synthesized?

Answer

5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione
5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione can be synthesized via the condensation of 3-hydroxybenzaldehyde with 1,3-diketone in the presence of a catalytic amount of an acid, such as acetic acid. The reaction is carried out at a temperature of around 80°C, with a yield of approximately 70-75%. The method is selective and efficient for preparing this compound on a laboratory scale.

About

CAS No 23204-36-6
English Name 5-Hydroxy-1H,3H-benzo[de]isochromene-1,3-dione
Molecular Formula C12H6O4
Molecular Weight 214.18 g/mol
SMILES C1=CC2=CC(=CC3=C2C(=C1)C(=O)OC3=O)O
InChIKey FKVNZFAMXGMPOU-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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