Compound Q&A
How is (4-Fluorophenyl)acetyl chloride (CAS: 459-04-1) typically synthesized?
Answer
(4-Fluorophenyl)acetyl chloride can be synthesized by the reaction of 4-fluorophenylacetic acid with thionyl chloride in the presence of a solvent such as ethanol or dioxane. The process typically involves heating to around 80°C and can yield up to 80% conversion with good selectivity.
About
CAS No
459-04-1
English Name
(4-Fluorophenyl)acetyl chloride
Molecular Formula
C8H6ClFO
Molecular Weight
172.59 g/mol
SMILES
C1=CC(=CC=C1CC(=O)Cl)F
InChIKey
SIOJFYRPBYGHOO-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
