Compound Q&A
How is 1-(Chloromethyl)-2-iodobenzene (CAS: 59473-45-9) typically synthesized?
Answer
1-(Chloromethyl)-2-iodobenzene is typically synthesized through a three-step process: first, 2-bromobenzaldehyde is treated with zinc chloride to form 1-chloromethyl-2-bromobenzene. Then, sodium iodide is used to replace the bromide ion, yielding the target compound. This synthesis involves the use of a fume hood due to the volatility and reactivity of the intermediate and final products.
About
CAS No
59473-45-9
English Name
1-(Chloromethyl)-2-iodobenzene
Molecular Formula
C7H6ClI
Molecular Weight
252.48 g/mol
SMILES
C1=CC=C(C(=C1)CCl)I
InChIKey
FTMNWZHKQGKKAU-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
