Compound Q&A

How is 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic acid (CAS: 7712-05-2) typically synthesized?

Answer

4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic acid
4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic acid can be synthesized through Friedel-Crafts acylation of 4,6-dihydrothieno[3,4-b]thiophene with acyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. The yield can reach up to 85% under optimal conditions. This method ensures high selectivity to the desired product.

About

CAS No 7712-05-2
English Name 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic acid
Molecular Formula C7H6O2S2
Molecular Weight 186.26 g/mol
SMILES C1C2=C(CS1)SC(=C2)C(=O)O
InChIKey RBINIIIGSUWMLQ-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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