Compound Q&A
How is (3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid (CAS: 331763-75-8) typically synthesized?
Answer
![(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid](https://static.chemtradehub.com/structs/331/331763-75-8-5a73.webp "(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid")
(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid is synthesized through a series of steps. Typically, it involves bromination of a phenol, followed by coupling with a protected amino acid derivative. The reaction is performed under mild conditions using a suitable catalyst to ensure high selectivity and yield. The final step involves deprotection, yielding the desired acid.
About
CAS No
331763-75-8
English Name
(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid
Molecular Formula
C15H20BrNO4
Molecular Weight
358.23 g/mol
SMILES
CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)Br)CC(=O)O
InChIKey
GYXZKHKUVVKDHI-GFCCVEGCSA-N
Last Updated: 2025-10-22 12:37
![(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![(3R)-4-(4-Bromophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid — ShangHaiChuangSai Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecce82b2de6e8e95a5e02/67cecce82b2de6e8e95a5e02-logo.webp){kind=logo}