Compound Q&A
How is 6-Bromo-1,3-benzoxazol-2-amine (CAS: 52112-66-0) typically synthesized?
Answer
6-Bromo-1,3-benzoxazol-2-amine is typically synthesized through the bromination of 1,3-benzoxazol-2-one followed by an aminolysis reaction. The bromination step often uses N-bromosuccinimide (NBS) in an organic solvent like dichloromethane. The aminolysis step involves treating the brominated product with an amine in a suitable solvent, such as ethanol or dimethylformamide (DMF).
About
CAS No
52112-66-0
English Name
6-Bromo-1,3-benzoxazol-2-amine
Molecular Formula
C7H5BrN2O
Molecular Weight
213.03 g/mol
SMILES
C1=CC2=C(C=C1Br)OC(=N2)N
InChIKey
APUYIVHTTCCVMF-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
