Compound Q&A

How is 1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-prolineHydrate (CAS: 64838-55-7) typically synthesized?

Answer

1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-prolineHydrate
1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-prolineHydrate is synthesized through a multi-step process involving acetylation, thiolation, and condensation reactions. The key steps include the acetylation of L-proline, followed by the introduction of a thiyl group, and finally coupling with the methylpropionyl moiety. Catalytic amounts of acetic anhydride and sodium hydride are typically used, with high yield and good selectivity in the reactions.

About

CAS No 64838-55-7
English Name 1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-prolineHydrate
Molecular Formula C11H17NO4S
Molecular Weight 259.33 g/mol
SMILES CC(CSC(=O)C)C(=O)N1CCCC1C(=O)O
InChIKey ZNQRGUYIKSRYCI-APPZFPTMSA-N
Last Updated: 2025-10-22 12:37

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