Compound Q&A
How is 4-bromo-7-fluoro-1H-indole (CAS: 883500-66-1) typically synthesized?
Answer
4-bromo-7-fluoro-1H-indole can be synthesized via a Knoevenagel condensation reaction of 7-fluoroindole with a bromoalkyl ketone, followed by purification. This method uses a Lewis acid as a catalyst, and the reaction yields are generally good. The process involves careful control of reaction conditions to achieve high selectivity towards the desired product.
About
CAS No
883500-66-1
English Name
4-bromo-7-fluoro-1H-indole
Molecular Formula
C8H5BrFN
Molecular Weight
214.04 g/mol
SMILES
C1=CC(=C2C=CNC2=C1F)Br
InChIKey
PBQKMEMSAFAVKF-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
