Compound Q&A
How is 2-Iodoisonicotinic acid (CAS: 58481-10-0) typically synthesized?
Answer
2-Iodoisonicotinic acid is typically synthesized by reacting nicotinic acid with iodine in the presence of a suitable catalyst, such as potassium carbonate. The reaction is carried out in a polar aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is usually around 80%, and the product is isolated by crystallization from aqueous solution.
About
CAS No
58481-10-0
English Name
2-Iodoisonicotinic acid
Molecular Formula
C6H4INO2
Molecular Weight
249.01 g/mol
SMILES
C1=CN=C(C=C1C(=O)O)I
InChIKey
FALCXGCLOUKBSP-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37
