Compound Q&A

How is N~2~-[(Benzyloxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine (CAS: 7733-29-1) typically synthesized?

Answer

N~2~-[(Benzyloxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine
N~2~-[(Benzyloxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine is typically synthesized through a multi-step process involving the protection of the amino group, followed by the introduction of the benzyloxy and 2-methyl-2-propanyl groups via esterification and amidation reactions. Commonly, triphenylphosphine and triethylamine are used as catalysts, and the overall yield is around 75-85%. This synthesis is performed under anhydrous conditions to avoid unwanted side reactions.

About

CAS No 7733-29-1
English Name N~2~-[(Benzyloxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-ornithine
Molecular Formula C18H26N2O6
Molecular Weight 366.41 g/mol
SMILES CC(C)(C)OC(=O)NCCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1
InChIKey RWQCKACYKKSOKK-AWEZNQCLSA-N
Last Updated: 2025-10-22 12:37

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