Compound Q&A
How is (4-Bromo-2-thienyl)methanol (CAS: 79757-77-0) typically synthesized?
Answer
(4-Bromo-2-thienyl)methanol is typically synthesized by reacting 2-bromothiophene with methanol in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) at elevated temperatures. The yield is generally around 70-80%, with good selectivity towards the desired product. The reaction is monitored by thin-layer chromatography (TLC) or nuclear magnetic resonance (NMR) spectroscopy.
About
CAS No
79757-77-0
English Name
(4-Bromo-2-thienyl)methanol
Molecular Formula
C5H5BrOS
Molecular Weight
193.07 g/mol
SMILES
C1=C(SC=C1Br)CO
InChIKey
PXZNJHHUYJRFPZ-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
