Compound Q&A
How is Ethyl (2E)-amino(hydroxyimino)acetate (CAS: 10489-74-4) typically synthesized?
Answer
Ethyl (2E)-amino(hydroxyimino)acetate can be synthesized via the Mannich reaction, where ethyl acetoacetate, an amine, and formaldehyde are reacted in the presence of an acid catalyst such as p-toluenesulfonic acid. The reaction yields the desired product with good to excellent selectivity and high yield, making it a suitable method for industrial synthesis.
About
CAS No
10489-74-4
English Name
Ethyl (2E)-amino(hydroxyimino)acetate
Molecular Formula
C4H8N2O3
Molecular Weight
132.12 g/mol
SMILES
CCOC(=O)C(=NO)N
InChIKey
QGYKRMZPOOILBA-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
