Compound Q&A

How is Hexyl methanesulfonate (CAS: 16156-50-6) typically synthesized?

Answer

Hexyl methanesulfonate
Hexyl methanesulfonate is typically synthesized by reacting hexanol with methanesulfonyl chloride in the presence of a base such as sodium hydroxide. The reaction proceeds via a nucleophilic substitution mechanism, where the hydroxyl group of hexanol is replaced by the methanesulfonate group. The yield is generally high, and the method is known for its good selectivity and operational simplicity.

About

CAS No 16156-50-6
English Name Hexyl methanesulfonate
Molecular Formula C7H16O3S
Molecular Weight 180.27 g/mol
SMILES CCCCCCOS(=O)(=O)C
InChIKey URIRDRHUUFRHAS-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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