Compound Q&A

How is Methyl 6-formylnicotinate (CAS: 10165-86-3) typically synthesized?

Answer

Methyl 6-formylnicotinate
Methyl 6-formylnicotinate (CAS: 10165-86-3) can be synthesized via the formylation of methyl nicotinate using a formylating agent such as formic anhydride in the presence of a catalyst like anhydrous aluminum chloride. The reaction involves the addition of formyl groups to the nicotinic acid structure, followed by esterification with methyl alcohol. The yield and selectivity of the reaction can be optimized by controlling the reaction conditions.

About

CAS No 10165-86-3
English Name Methyl 6-formylnicotinate
Molecular Formula C8H7NO3
Molecular Weight 165.15 g/mol
SMILES COC(=O)C1=CN=C(C=C1)C=O
InChIKey BZOWIADSJYMJJJ-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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