Compound Q&A
How is 3,4-Dichloro-1,2-thiazole-5-carboxylic acid (CAS: 18480-53-0) typically synthesized?
Answer
3,4-Dichloro-1,2-thiazole-5-carboxylic acid is commonly synthesized through the condensation of chloroacetyl chloride with 2-chlorothiazole. The reaction proceeds via a nucleophilic substitution and condensation mechanism, yielding a high yield of the desired product. This process often involves the use of a basic catalyst to enhance the reaction selectivity.
About
CAS No
18480-53-0
English Name
3,4-Dichloro-1,2-thiazole-5-carboxylic acid
Molecular Formula
C4HCl2NO2S
Molecular Weight
198.03 g/mol
SMILES
C1(=C(SN=C1Cl)C(=O)O)Cl
InChIKey
HQZKNCJWLIWCSV-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
