Compound Q&A
How is 4-(Chloromethyl)-2-methyl-1,3-thiazole hydrochloride (CAS: 77470-53-2) typically synthesized?
Answer
4-(Chloromethyl)-2-methyl-1,3-thiazole hydrochloride is typically synthesized by the reaction of 2-methyl-1,3-thiazole with hydrogen chloride under reflux conditions. The reaction is catalyzed by a trace amount of a Lewis acid, and the yield is usually around 85%. The product is isolated by recrystallization from water.
About
CAS No
77470-53-2
English Name
4-(Chloromethyl)-2-methyl-1,3-thiazole hydrochloride (1:1)
Molecular Formula
C5H7Cl2NS
Molecular Weight
184.09 g/mol
SMILES
CC1=NC(=CS1)CCl.Cl
InChIKey
YGKDISJLDVGNOR-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
