Compound Q&A
How is 5-Bromo-2-chloronicotinamide (CAS: 75291-85-9) typically synthesized?
Answer
5-Bromo-2-chloronicotinamide (CAS: 75291-85-9) is typically synthesized by the bromination of 5-chloronicotinamide followed by the substitution of the chlorine atom with bromine. The reaction involves the use of bromine in the presence of appropriate bases or catalysts to achieve high selectivity and yield. The process often requires careful control of reaction conditions to avoid overbromination.
About
CAS No
75291-85-9
English Name
5-Bromo-2-chloronicotinamide
Molecular Formula
C6H4BrClN2O
Molecular Weight
235.47 g/mol
SMILES
C1=C(C=NC(=C1C(=O)N)Cl)Br
InChIKey
NFUOTGWWIKJNQL-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
