Compound Q&A

How is [4-Fluoro-3-(trifluoromethyl)phenyl]methanol (CAS: 67515-61-1) typically synthesized?

Answer

[4-Fluoro-3-(trifluoromethyl)phenyl]methanol
[4-Fluoro-3-(trifluoromethyl)phenyl]methanol can be synthesized through a one-pot reaction of 4-fluoro-3-(trifluoromethyl)benzaldehyde with methanol in the presence of a base like sodium hydroxide. The reaction is carried out under mild conditions to ensure high selectivity and yield. This method is commonly used in academic and industrial settings for the preparation of this compound.

About

CAS No 67515-61-1
English Name [4-Fluoro-3-(trifluoromethyl)phenyl]methanol
Molecular Formula C8H6F4O
Molecular Weight 194.13 g/mol
SMILES C1=CC(=C(C=C1CO)C(F)(F)F)F
InChIKey DGBDVJVPBJMVDH-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

Related Q&A

Compound Q&A

What are the physical and chemical properties of [4-Fluoro-3-(trifluoromethyl)phenyl]methanol (CAS: 67515-61-1)?

[4-Fluoro-3-(trifluoromethyl)phenyl]methanol is a colorless to white crystalline solid at room tempe...

Compound Q&A

What industries use [4-Fluoro-3-(trifluoromethyl)phenyl]methanol (CAS: 67515-61-1)?

[4-Fluoro-3-(trifluoromethyl)phenyl]methanol is widely used in the pharmaceutical industry as an int...

Compound Q&A

What precautions should be taken when handling [4-Fluoro-3-(trifluoromethyl)phenyl]methanol (CAS: 67515-61-1)?

When handling [4-Fluoro-3-(trifluoromethyl)phenyl]methanol, it is essential to use appropriate perso...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...