Compound Q&A

How is 5-bromo-7-fluoro-1H-indole (CAS: 883500-73-0) typically synthesized?

Answer

5-bromo-7-fluoro-1H-indole
5-Bromo-7-fluoro-1H-indole can be synthesized via a multistep process involving bromination and fluorination of 1H-indole. Commonly, the bromination is carried out using bromine in the presence of a Lewis acid catalyst like aluminum bromide. The fluorination step typically utilizes hydrogen fluoride or trifluoroacetic anhydride. The overall yield and selectivity depend on the specific reaction conditions and catalysts used.

About

English Name 5-bromo-7-fluoro-1H-indole
Molecular Formula C8H5BrFN
Molecular Weight 214.04 g/mol
SMILES C1=CNC2=C(C=C(C=C21)Br)F
InChIKey TZRRRWOVYVGRSL-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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