Compound Q&A

How is Abarelix (CAS: 183552-38-7) typically synthesized?

Answer

Abarelix
Abarelix is synthesized through a multi-step process involving the construction of key peptide segments and their subsequent coupling. Common synthetic methods include solid-phase peptide synthesis (SPPS) followed by purification steps such as HPLC. The synthesis typically requires standard laboratory equipment and reagents, with careful monitoring of reaction progress and product purity.

About

English Name Abarelix
Molecular Formula C72H95ClN14O14
Molecular Weight 1416.09 g/mol
SMILES CC(C)CC(C(=O)NC(CCCCNC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)N(C)C(=O)C(CO)NC(=O)C(CC3=CN=CC=C3)NC(=O)C(CC4=CC=C(C=C4)Cl)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)NC(=O)C
InChIKey AIWRTTMUVOZGPW-HSPKUQOVSA-N
Last Updated: 2025-10-19 20:30

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